I've seen a few of these cartoons from time to time, the stupid Watson one in particular has entertained me several times before. However, many of these were unknown or barely known to me and I greatly enjoyed turning the page to see what it had in store for me next.
A few that stand out in my memory are:
a couple of Macbeth ones - Unsex me, sex me and Hell is murky.
the Crime and Punishment ones - Raskolnikov
and the one introducing me to Rosalind Franklin.
This book immediately went on my To Buy list and I've been enjoying the website quite a bit.